Best answer
Changing the local environment of reactants
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What is the role of activation energy in enzyme activity?
Activation energy is needed to break down chemical bonds allowing the reaction to occur. When an enzyme binds to a substrate, it lowers the substrate molecules鈥?energy to react to form products. This increases the chance of the reaction occurring and therefore increases the rate of reaction.
How do enzymes lower the energy needed for a chemical reaction?
By manipulating the substrates of the reaction, the enzyme can lower the necessary energy needed to make the reaction occur. The enzyme itself is not a component of the chemical reaction and is the same molecule at the beginning of the reaction as it is at the end.
What is the role of binding energy in enzyme-substrate reactions?
Binding energy is the primary energy source used by the enzyme to lower the activation energy. So the key aspect of the enzyme-substrate reaction is that the enzyme reduces the activation energy for this reaction, thereby augmenting the rate. The binding energy provides this.
How does an enzyme act to lower Ea?
An enzyme can act in several ways to lower Ea. It does this by forming an enzyme-substrate (ES) complex. 1. The enzyme may hold the substrates in such a way as to distort the substrate bonds closer to their form in the transition state.